Ph.D. (Biochemistry and Molecular Biology), August 2002, Penn State University College of Medicine
B.S. (Biology), December 1994, Indiana University of Pennsylvania
BIO 101 - Bioterrorism
BIO 112 - Cell Biology
BIO 316 - Virology
BIO 319 - Genetics
BIO 405 - Molecular Biology
M. Blome, B.C. Yowler, R. O'Keeffe, N. Panjwani, A.M. Pickett, and C-L. Schengrund. (2008) Use of surface plasmon resonance to characterize binding of botulinum type A toxin-haemagglutinin complex to gangliosides. The Botulinum Journal.
Petro, K.A., Dyer, M.A., Yowler, B.C., and Schengrund, C-L. Disruption of lipid rafts enhances activity of botulinum neurotoxin serotype A. Toxicon. 48: 1035-1045. (2006)
Yowler, B.C., and Schengrund, C-L. Glycosphingolipids-Sweets for botulinum neurotoxin. Glycoconjugate Journal. 21: 285-291. (2004)
Yowler, B.C., and Schengrund, C-L. Kinetic analysis of the interaction of Botulinum neurotoxin with ganglioside GT1b. Biochemistry 43: 9725-31. (2004)
Kensinger, R.D., Yowler, B.C., Benesi, A.J., Schengrund, C-L. Synthesis of novel, multivalent, glycodendrimers as Ligands for HIV-1 gp120. Bioconjugate Chemistry 15:349-58. (2004)
Yowler, B.C., Kensinger, R.D., and Schengrund, C-L. Botulinum neurotoxin A activity is dependent upon the presence of specific gangliosides in neuroblastoma cells expressing synaptotagmin I. Journal of Biological Chemistry 277:32815-32819. (2002)
Yowler, B.C., Stoehr, S.A., and Schengrund, C-L. Oxidation and base-catalyzed elimination of the saccharide portion of GSLs having very different polarities. Journal of Lipid Research 42:659-662. (2001)
Ropson, I.J., Yowler, B.C., Dalessio, P.M., Banaszak, L.B., and Thompson, J. Properties and Crystal Structure of a B-Barrel Folding Mutant. Biophysical Journal 78:1551-1560. (2000)
Research on Recovery from Botulinum Toxin Paralysis: This project attempts to determine whether there is a difference in time of onset or time of recovery from leg paralysis due to botulinum toxin poisoning in running vs. non-running mice.
Research on the detection of CAEV, an HIV-like virus in dairy goats. This project involves testing a variety of bodily fluids to determine the possible routes of transmission of the virus.
Miscellaneous, e.g., hobbies, sports, personal info, etc.
Currently the Head Coach for Men’s and Women’s Cross Country and Track and Field
Married with 2 young children
Enjoy distance running - have raced 17 marathons and counting (including Boston)