Geneva College

 

 

Brian C. Yowler

Brian YowlerOffice Phone: 724-847-6728
bcyowler@geneva.edu          

Disciplines/Field of Instruction

  • Biochemistry/Biology

Degrees Received

  • Ph.D. (Biochemistry and Molecular Biology), August 2002, Penn State University College of Medicine
  • B.S. (Biology), December 1994, Indiana University of Pennsylvania

Courses Taught

  • BIO 101 - Bioterrorism
  • BIO 112 - Cell Biology
  • BIO 316 - Virology
  • BIO 319 - Genetics
  • BIO 405 - Molecular Biology

Presentations/Publications

  • M. Blome, B.C. Yowler, R. O'Keeffe, N. Panjwani, A.M. Pickett, and C-L. Schengrund. (2008) Use of surface plasmon resonance to characterize binding of botulinum type A toxin-haemagglutinin complex to gangliosides. The Botulinum Journal.
  • Petro, K.A., Dyer, M.A., Yowler, B.C., and Schengrund, C-L.  Disruption of lipid rafts enhances activity of botulinum neurotoxin serotype A. Toxicon. 48: 1035-1045. (2006)
  • Yowler, B.C., and Schengrund, C-L. Glycosphingolipids-Sweets for botulinum neurotoxin. Glycoconjugate Journal. 21: 285-291. (2004)
  • Yowler, B.C., and Schengrund, C-L. Kinetic analysis of the interaction of Botulinum neurotoxin with ganglioside GT1b. Biochemistry 43: 9725-31. (2004)
  • Kensinger, R.D., Yowler, B.C., Benesi, A.J., Schengrund, C-L. Synthesis of novel, multivalent, glycodendrimers as Ligands for HIV-1 gp120.  Bioconjugate Chemistry 15:349-58. (2004)
  • Yowler, B.C., Kensinger, R.D., and Schengrund, C-L.  Botulinum neurotoxin A activity is dependent upon the presence of specific gangliosides in neuroblastoma cells expressing synaptotagmin I.  Journal of Biological Chemistry 277:32815-32819. (2002)
  • Yowler, B.C., Stoehr, S.A., and Schengrund, C-L.  Oxidation and base-catalyzed elimination of the saccharide portion of GSLs having very different polarities. Journal of Lipid Research 42:659-662. (2001)
  • Ropson, I.J., Yowler, B.C., Dalessio, P.M., Banaszak, L.B., and Thompson, J.  Properties and Crystal Structure of a B-Barrel Folding Mutant. Biophysical Journal 78:1551-1560. (2000)

Current Projects

  • Research on Recovery from Botulinum Toxin Paralysis: This project attempts to determine whether there is a difference in time of onset or time of recovery from leg paralysis due to botulinum toxin poisoning in running vs. non-running mice.
  • Research on the detection of CAEV, an HIV-like virus in dairy goats. This project involves testing a variety of bodily fluids to determine the possible routes of transmission of the virus.  

Miscellaneous, e.g., hobbies, sports, personal info, etc.

  • Currently the Head Coach for Men’s and Women’s Cross Country and Track and Field
  • Married with 2 young children
  • Enjoy distance running - have raced 17 marathons and counting (including Boston)
  • Avid Pittsburgh Sports fan

 

Point of Excellence

Geneva prepares students for a wide range of environmental careers through a B.S. degree in environmental science and an engineering concentration in environmental technology.

more points >>
 
Upcoming Events
COMMUNITY
Red Cross presents Geneva the College of the Year Award
The campus community was honored for its support of the Red Cross Blood Program.
ATHLETICS
Super Fans bring back GT Victory Bell ring
The tradition was restored in honor of the volleyball win against Chatham.
ACADEMICS
Geneva leaps ahead in U.S. News 2015 Best College rankings
This year, Geneva climbs even higher in the Best Value, Best Regional College and Best Engineering lists.
STUDENT LIFE
Alexander Dining Hall completed
After a summer of renovation, the changes to Alexander Dining Hall are finished.
CAMPUSWIDE EVENTS
Academic Convocation officially opened the fall semester
First-year students were welcomed and faculty achievements were honored during the traditional ceremony.