Angela Johnson

Disciplines/Field of Instruction

• Biology

Degrees Received

• Ph.D., 2008, Pathology, Case Western Reserve University, Cleveland, OH
• B.S., 2001, Biology, Geneva College, Beaver Falls, PA

Courses Taught

• BIO 112 - Cell Biology
• BIO 120 - Fundamental Human Anatomy and Physiology I (labs)
• BIO 121 - Fundamental Human Anatomy and Physiology II
• BIO 225 - Human Anatomy and Physiology I
• BIO 315 - Immunology

Presentations / Publications

• Alexandria David, Megan MacLeod, Angela C. Johnson, Philippa Marrack and Trine N. Jørgensen. 2014. Intrinsic autoimmune capacities of hematopoietic cells from female New Zealand hybrid mice. Genes and Immunity. 15 (3): 153-161. (PMID: 24477163)
• Angela C. Johnson, Ayesha Khan, Elena Gonzalez, Laura M. Davison, Xiaoxia Li, and Trine N. Jorgensen. Lack of IRAK4 leads to systemic abscess formation and early lethality but does not impair autoimmunity in Act1-deficient mice. 2014. Annual Meeting of the Federation of Clinical Immunology Societies (FOCUS), Chicago, Illinois.
• Angela C. Johnson, Laura Davison, Natalia V. Giltiay, Chairut Vareechon, Xiaoxia Li and Trine N. Jørgensen. 2012. Lack of T cells in Act1-deficient mice results in elevated IgM-specific autoantibodies but reduced lupus-like disease. European Journal of Immunology. 42 (7): 1695-1705. (PMID: 22585710)
• Angela C. Johnson, Xiaoxia Li, and Trine N Jorgensen. T cells, but not TLRs, control Act1-driven autoimmunity. 2010. Annual Meeting of the American Association of Immunologists, Baltimore, Maryland.
• Trine N. Jørgensen, Natalia V. Giltiay, Angela Johnson, Xiaoxia Li. 2009. “Chapter 4: The role of Act1 in the control of autoimmunity” in The Epigenetics of Autoimmune Disease. Editor: Moncef Zouali, Publisher: John Wiley & Sons, Inc. ISBN: 9780470758618.
• Angela C. Johnson, Xiaoxia Li, and Eric Pearlman. 2008. MyD88 functions as a negative regulator of TLR3/TRIF-induced corneal inflammation by inhibiting activation of c-Jun N-terminal kinase. Journal of Biological Chemistry. 283 (7): 3988-3996. (PMID: 18057004).
• Eric Pearlman, Angela C. Johnson, Gautam Adhikary, Yan Sun, Holly R. Chinnery, Todd Fox, Mark Kester, and Paul G. McMenamin, 2008. Toll-like Receptors at the ocular surface. The Ocular Surface. 6 (3): 108-116. (PMID: 18781257)
• Angela C. Johnson, Megan K. L. Macleod, Alexandria David, Philippa Marrack, and Trine N. Jorgensen. Gender-Related Differences in the Bone Marrow of Lupus-Prone Mice. 2008. Lupus Autoimmunity: Mechanisms and Immune Regulation, Biosymposia, Inc., La Jolla, California.
• Natalia Giltiay, Youcun Qian, Angela C. Johnson, Trine N. Jorgensen, and Xiaoxia Li. Act1-Deficient Mice as a Model of SLE: Insights into the Cellular and Molecular Mechanisms of the Disease Development. 2008. Lupus Autoimmunity: Mechanisms and Immune Regulation, Biosymposia, Inc., La Jolla, California.
• Angela C. Johnson, Yan Sun, and Eric Pearlman. MyD88 negatively regulates TLR3/TRIF-induced corneal inflammation through c-Jun N-terminal kinase (JNK). 2007. Society for Leukocyte Biology, Annual Meeting of the Society for Leukocyte Biology, Boston, Massachusetts. (Selected oral presentation, Presidential Student Award)
• Angela C. Johnson, Fred P. Heinzel, Eugenia Diaconu, Yan Sun, Amy G. Hise, Douglas Golenbock, Jonathan H. Lass, and Eric Pearlman. 2005. Activation of Toll-Like Receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation. Investigative Ophthalmology and Visual Sciences. 46 (2): 589-595. (PMID: 15671286)
• Angela C. Johnson and Eric Pearlman. 2005. Toll-like Receptors in the cornea. The Ocular Surface. 3 (4): S187-S189. (PMID: 17216116)

Current Projects

• Understanding Innate Immune mechanisms of the body, specifically macrophages, Toll-like Receptors, and cytokines.

Affiliations

• Center for Bioethics and Human Dignity
• American Association of Immunologists

Committees

• Pre-Med Committee
• Faculty Policy and Development Committee
• Biology Department Search Committee
• Department Chair
• Campus Leadership Group

Miscellaneous

• I enjoy reading, cooking, and spending time with my husband and three children.
• Our family attends Pathway Church.